Our present work was undertaken to apply specially engineered fiber-optic based nano-probes for the precise delivery of laser light on to a single cell and to observe production of low power laser light induced reactive oxygen species (ROS).
All these results, along with minimal in vitro and in vivo toxicity profiles, suggest potential of the iRGD-based activatable monolithic peptide probe as a promising imaging agent for precise tumor diagnosis.
This method of data acquisition allows for real time optimization of optomechanical transduction in our devices, which facilitates sensitive probing of their mechanical motion, allowing for precise measurements of physical quantities, such as forces [18] and torques [21].
AFM experiments were carried out with a Nanowizard II (JPK Instruments, Berlin, Germany) equipped with nano-positioning sensors in all three axis and closed-loop feedback for precise, repeatable scanning and probe positioning with sub-nanometer resolution.
Considering the fiber and lens assembly and the micromotor and microreflector assembly are separate from each other at the distal end of the probe, special care needs to be taken for precise alignment, centering, and stabilization of the two assemblies.
The provision of an ultrasound probe in close proximity to the biliary tree allows for precise high-resolution imaging of the gallbladder.
For precise and complete insertion of these neural probes in the cortex an insertion tool was developed, which can be attached to a variety of different electrode drives.
Results: In the first group of patients, the finger-grip probe provided precise location of the leiomyomas and intraoperative guidance for dissection during the myomectomy.
These functions allow for precise field measurements.
