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The mechanisms by which p53 exerts an antilipogenic effect on cells seem complex and are probably multifaceted.
Reasons for the observed occurrences of blastomycosis, coccidioidomycosis, and histoplasmosis outside areas to which they are traditionally classified as endemic are unclear but are probably multifaceted.
However, depending on the animal model, deletion of microsomal PGE2 synthase-1 can either prevent or accelerate tumorigenesis, indicating that the contribution of COX-2 to cancer, particularly to cellular transformation, is probably multifaceted.
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The functional contribution is most likely multifaceted.
Patient adherence to follow-up recommendations is probably a multifaceted phenomenon [ 4, 5].
Domingue said the actual mechanism for a person being drawn to another person's genetic similarities is probably complicated and multifaceted - "just a whole host of things," he noted.
Given recent developments in our understanding of its molecular properties, VitD probably has a multifaceted role, which cannot be appreciated by examining hard clinical endpoints such as mortality.
In order to do this, a multifaceted approach is probably needed, with guidance from experts in qualitative research.
While this affirmation appears probably too deterministic to describe the multifaceted reality, it is true that there are proxy indicators suggesting that sophisticated criminal networks are exploiting wildlife as source of profit, especially in its most lucrative areas such as caviar smuggling (Cook et al. [2002]; Cooper [2006] IFAW [2008]]) and the fur trade (according to two interviewees).
For the implementation of guidelines, multifaceted implementation strategies are probably more effective than single strategies, as multifaceted strategies address multiple barriers to guideline adherence [ 16].
The short (and theoretical) answer is probably no — perhaps most people are so multifaceted and evolving that each year inevitably brings a new consciousness, and fresh ideas about what it means to be alive.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com