Identifying patients who are probable non-responders to the standard dosing regimen and/or patients with an increased risk of adverse drug reactions has a major impact on the benefit risk ratio of a drug at an individual level.
True levels of knowledge may even be lower than those reported, as survey response rates tend to be around 70% and it is probable that non-responders would have lower knowledge than responders.
It is very probable that non-responders and women who were not reachable are at higher risk of exposure to HPV.
A subgroup of probable iNPH patients responds favorably to VP shunt insertion but for a brief period (temporary responders).
Results of the receiver operating characteristics (ROC) analysis indicated that the RMI score with a cut-off 136 or less performed only slightly better than chance in delineating probable malingerers from valid responders in this setting.
WTC-responders with probable PTSD had highly elevated ORs for probable depression (OR = 13.9; 95% CI, 11.9 16.2) and panic disorder (OR = 9.2; 95% CI, 7.6 11.1).
For example, approximately one-third of the responders without probable PTSD reported disturbing memories, thoughts, or images; having trouble falling asleep or staying asleep, and being "super-alert".
Among the responders with probable PTSD, 12.7% also met criteria for panic disorder or depression, and 1.7% met criteria for all three disorders: probable PTSD, depression, and panic disorder.
Nearly half (45%) of all responders without probable PTSD reported suffering from a substantial stress reaction as long as 5 years after the WTC disaster, a rate comparable to the nationally representative sample of U.S. adults surveyed only 3 5 days after the attacks when symptoms typically are at their highest level (Silver et al. 2002).
We classified a responder as having probable PTSD if the score was ≥ 44 or ≥ 50, where each item was scored as 1 5 (corresponding respectively to not at all, a little bit, moderately, quite a bit, or extremely).
Evaluees were assigned to one of two groups; probable malingerers (PM; n = 30) and a group of valid test responders (n = 30) (1999).
