Exact(3)
The probability Elsasser number corresponds to the most probable force ratio bin, Λ P =0.12.
Outside this range of velocities, the kinetic parameters extracted by using the standard most probable force approach might be interpreted as artificial energy barriers that are not present in the actual energy landscape.
A histogram was constructed for the number of adhesion events recorded on TiO2 (110) surface (total number of events: n ≈ 60) versus rupture force and was used to obtain the most probable force (MPF), which was 128.31 ± 38.88 pN (Fig. 2b).
Similar(57)
Usually, the dependency of the most probable rupture force on the force rate or the shape of the rupture force histogram is fitted with different models that contain approximations and basic assumptions.
The force-distance curves were analyzed and plotted in a histogram of unbinding events to determine the probable unbinding force.
The results showed two regimes in the plot of the most probable unbinding force versus the logarithm of the loading rate, revealing the presence of two (at least) activation barriers.
The most probable rupture force is then proportional to the natural logarithm of the loading rate [ 17, 18].
The major probable driving force behind this association is vitamin B12, which the algae needs for growth but cannot synthesize.
The most probable rupture force for single events was ~104 pN, while for double events this value was ~140 pN at a pulling speed of 800 nm/s.
The most probable unbinding force [ 29] was found to be similar for both of the testosterone-sbAvd complexes: 40 pN at a constant pulling velocity of 600 nm/s.
Recently, the mechanical unfolding kinetics of the native to intermediate (N→I) transition of the protein filamin was characterized in a broad range of pulling velocities (1 4000 nm/s), and an unexpected plateau in the modal (i.e., most probable) unfolding force, F∗, was observed at low pulling velocities/loading rates (Fig. 1) (5).
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