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The Guy's Group (abstract #144 [ 1]) with the MRC Cancer Trials Unit presented their estimates for overall survival probabilities and probable benefit for adjuvant systemic therapy (both hormonal and chemotherapy).
Also, the agency has licensed two total artificial hearts: SynCardia Cardiowest for bridge to transplant and Abiomed Abiocor on a "probable benefit" basis.
"Its only probable benefit would be to remind people that they're late for work -- again," Mr. Molinari said about the clock, which would have greeted Staten Islanders crossing the harbor.
Companies applying for humanitarian device approval can conduct much smaller clinical trials — Second Sight submitted data on only 30 patients — and must only demonstrate safety and "probable benefit," not proof of effectiveness, Dr. Eydelman said.
"However, per the FDA definition, it is approved based on evidence of safety and probable benefit".
1) Offering an approach to evaluate the probable benefit of a company which is in charge of the ADS regional energy service considering its investment and operation cost.
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Instead of thinking up wise ways to invest these funds, officials used construction projects simply to inject money into rural areas with insufficient regard for the probable benefits.Hokkaido has little to show for all this public investment.
Even the army may have decided that the costs of backing the insurgency in Kashmir now outweigh the probable benefits.Pakistani diplomats were privately amazed at how easily the talks had gone.
Fanger, B.W. Olesen, C.J.K. Pedersen, The mental performance of subjects clothed for comfort at two different air temperatures, Ergonomics 18 (1975) 358 374; D.P. Wyon, Individual microclimate control: required range, probable benefits and current feasibility, in: Proceedings of Indoor Air '96, Institute of Public Health, Tokyo, 1996; D.P. Wyon, Indoor environmental effects on productivity.
The level of minimum robustness required also depends on the probable benefits of the organism.
Such findings suggest probable benefits in discussing end of life preferences while well, before death seems close.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com