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Further, their theoretical predictions for probable activities have been taken using PASS (Prediction of Activity Spectra for Substance).
Some possible candidates for all four series were designed and their probable activities were estimated by using different QSAR models.
Type of exposure was classified on the basis of the most probable activities of risk (n = 410).
It can be seen from the results of PASS that most probable activities are antioxidant, antiproliferative and hepatoprotectants.
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Consensus predictions made by both the models suggested 11 molecules to have probable activity against miR-21.
Moreover, it has shown higher probable activity value for scavenging free radical along with anti-dementia effects, predicted by PASS online computer program.
The predicted activity spectrum of a compound is estimated as probable activity (Pa) and probable inactivity (Pi) and only activities with Pa > Pi are considered.
AluSx shows the most expanded activity with the 75% interval of probable activity overlapping that of both the AluJ elements and the other AluS subfamilies.
Studying the reaction use and fluxes involving these compounds will help us understand the probable activity in amino acid biosynthesis and degradation pathways.
It was selected four groups of ten mice each for further investigation the probable modulatory activities of opioid receptors on the anticonvulsant activity of Pasipay [ 27, 28].
Considering the predominant protein composition (670 μg protein/mg of crude venom) in the P. bistriata venom, we chose to investigate the probable enzymatic activities of these proteins, testing mainly for phospholipase A2 and proteolytic activity with a number of different specific substrates.
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