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We found that bi-directional gene pairs show a higher probability to be functionally associated, formulating hypotheses that the requirement for co-regulation of functionally related genes is a possible cause for the observed co-expression of bi-directional genes.
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For this reason, we focused our analysis also on other centrality metrics (i.e., betweenness, closeness, radiality, stress): in biological terms, these may be interpreted as the probability of a protein to be functionally relevant for other proteins and its functional ability to connect different cell nodes.
Based on these data we can consider for example that gene pairs with conserved neighborhood correlation score above 200 have a probability of approximately 80% to be functionally related.
They have to be functionally equivalent campuses.
A similar number have been found to be "functionally obsolete".
And the Medicare bill restricts Medicare from declaring drugs to be functionally equivalent in the future.
Macrophages are considered to be functionally heterogeneous cells with different phenotypes representing distinct sublineages [1],[2].
The rules have evolved over time in such a way to be functionally best.
There are currently 67 million adults living the UK, 8 million of which are considered to be functionally illiterate.
I was still too fat to be functionally gay.
The bird was assumed to be functionally extinct.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com