There was a significant effect of probability of trial type prediction for five trial types (NALR, DALR, VDRL, NARL and DARL) in episodic replays (ANOVA, P < 0.01).
To perform an analysis for replays, I analyzed the probability of trial type prediction across all replays occurring at the junction on a time-window basis.
To simulate reporting bias affecting trials in a given meta-analysis, we considered a selection model that links the probability of trial selection to both trial size and intensity of treatment effect [ 9, 31, 32].
There was a significant effect of the probability of trial-type prediction for five trial types (NALR, DALR, VDRL, NARL, and DARL) in episodic replays (ANOVA, p < 0.01; Figure 7 figure supplement 3).
To further check whether the predicted and actual trial types were coincidently matched, the probability of trial-type prediction across all replays occurring at the junction was analyzed on a time-window basis.
Secondly, to check whether matches between predicted and actual trial types were coincidental, I analyzed the probability of trial type prediction across all replays occurring at the junction on a time-window basis.
We further examined whether the degree of reinforcement-related speeding (mean reaction time on 90% probability of reinforcement trials – mean reaction time of 10% probability trials, and mean RT on 90% probability trials – mean RT on 50% probability trials) correlated with spatial working memory performance in patients.
Therefore, a decision to stop these trials using CP ⩽15%, suggests 16 and 22% probability of the trials continuing (Table 3); that is, the converse percentages.
"Research suggests that the probability of completed trials being published is roughly 50%.
We believe that, in the end, Genentech and our shareholders will profit from this type of research, because the probability of our trials' working and our general success rate will be higher".
For example, the probability of NoGo trials, and thereby the demand on response inhibition capacities, varies largely among these ERP studies just as in the studies investigating behavioral accuracy.
