Sentence examples for probability of substitution from inspiring English sources

Alternatively, natural selection may cause rate heterogeneity among loci and lineages via purifying selection that reduces the probability of substitution due to functional constraint or through the increased probability of substitution associated with positive natural selection [ 3- 6].

where Δ = difference in DssH's of subsequent sites, P xy = probability of substitution from state x to state y in site l, N = normally distributed, = probability of substitution from state x to state y in site l+1.

Maximum composite likelihood estimation of the probability of substitution from one base (row) to another base (column) instantaneously.

The Blosum62 score for substitution from serine to proline is -1 (range from -4 to +11; low to high probability of substitution) [ 17].

We first study how individual evolutionary events along specific branches of the phylogenetic tree relate to the probability of substitution in human.

In our paper we provide a rough estimate of the probability of substitution errors based on our data (see Additional Information [Additional file 1]).

Figure 5 shows amino acid property substitution matrices for the four types of variants in which the probability of substitutions is represented as heat maps.

It is also possible that meiotic recombination influences the fixation probabilities of substitution rates through gBGC.

The authors suggest the importance of using the appropriate model for probabilities of substitution among different amino acids or nucleotides, as well as the assumption of varying rates across sites.

The matrices A e represent the conditional probabilities of substitution between the states in B from the parent node pa e) to the child node ch e) of e.

BMG reconstructs the maximum likelihood of evolutionary history of the extant sequences, and then it analyzes the joint probability distribution of substitution events among sites in the sequences through a Bayesian graph model.