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What was my probability of progressing if I followed this strategy?
Benign lesions with atypical nuclei have about a fivefold higher probability of progressing to cancer than those with typical nuclei.
and using the probability of progressing from one state of affairs to the next.
A larger difference arises when we consider the probability of progressing from latency to active disease in each of the models.
In a model with exponential lifespans, the probability of progressing from latency to active disease is up to twice as likely (Fig. 2A).
For children under five years of age from medium/high transmission areas, all but 4 panellists estimated that the probability of progressing to severe malaria was 30% or less; however, one panellist estimated the risk to be 80%.
With constant lifetimes, the number of recent infections is greater due to the larger pool of susceptible individuals and the number of cases due to reactivation or reinfection is also greater due to the increased probability of progressing from latency to disease.
Cells with damaged DNA frequently arrest, which reduces the probability of progressing to malignancy.
A large majority of nevi have oncogenic BRAF mutations, but have a low probability of progressing to melanoma.
Individuals who had previously been infected had an increased probability of progressing to more severe manifestations of disease, i.e., DHF/DSS than those who were dengue-naive.
Parameters that determined mean tumour shrinkage and probability of progressing for non-growth reasons were varied between the two treatments in the case of randomised trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com