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In patients with an intermediate probability of persistent arthritis, we will study Disease Modifying Antirheumatic Drug of various intensities.
Treatment will be stratified according to the probability of persistent arthritis, and different combinations of treatment per stratum will be evaluated.
In patients with a high probability of persistent arthritis, we will study combination Disease Modifying Antirheumatic Drug therapy compared to monotherapy methotrexate.
Considering all 120 treated patients, there was a 15% probability of persistent neurological toxicity 6 months after the end of chemotherapy.
Our model focuses on the savings to be achieved by reducing the probability of persistent conduct disorder for children with the most severe conduct problems.
42, 44 The presence of a somatic RET (M918T) mutation correlates with higher probability of persistent disease and lower survival rate in a long-term follow up.
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We find that the gap (a_{t}^-a_{t}^) between the probabilities of persistent, high growth and persistent, high decay provides a good metric for particularly negative (if the gap is negative) or positive shocks that perturb countries on their path to convergence.
15 For this analysis we included the high probability stratum (>70% probability of developing persistent arthritis).
The presence of ACPA or RF 75 106– 109 111– 115 also increased the probability of developing persistent synovitis or a worse radiographic outcome.
The range of probabilities to which this translated lay between a 10% probability of developing persistent arthritis when one point was scored, and a 99% probability when 13 points were scored.
"Century-long observed trends … strongly suggest that anthropogenic forcing has increased the probability of severe and persistent droughts in this region.
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