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She argues that globalization has directly contributed to the emergence of pathogens such as the severe acute respiratory syndrome (SARS) coronavirus and is increasing the probability of pandemic influenza.
The treat-only program was slightly more cost-effective in the summer than the winter or midwinter as the probability of pandemic influenza being the cause of ILI was higher (96%, 89%, and 84%, respectively).
The total number of travellers during the pandemic must not exceed 115 (for R0 = 3.0) or 380 (for R0 = 1.5) if a PICT aims to keep the probability of pandemic arrival below 50%.
Notwithstanding the high level of assortativity observed in contact patterns data by age, that increase the probability of pandemic extinction, the model explains the spread at the global level observed in the 2009 H1N1 pandemic as induced by the interplay between the heterogeneity of the air mobility network structure, favoring the spread, and the population partition.
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In each of these cases the probability of pandemics such as those observed in Figure 2A is reduced either by reducing the strength of social learning (s = 0.1) or reducing the frequency of social learning events (cp = 0.01 or m = 5).
Furthermore, in view of recent events in east Asia, the probability of a pandemic has probably risen to >3 per 100 years, and new strains may prove more pathogenic than previous pandemic strains.
Based on the available data from the last three pandemics, Crowe and colleagues [ 19] estimated that there is a 2% probability of a pandemic (PrP = .02) in any given year, and pandemic flu incidence ranged from 9% to 35%, compared to 4%to6%6% in non-pandemic years.
Therefore most island nations may need to plan for multiple additional interventions (e.g., screening and quarantine) to raise the probability of remaining pandemic free or achieving substantial delay in pandemic arrival.
This analysis showed that the most important parameters were the severity of the pandemic (illness and death rates) and the annual probability of a pandemic.
We adjusted all cost-benefit outcomes for the estimated probability of a pandemic occurring per year.
Even under the most unfavorable estimates, prepandemic stockpiling remained cost-saving as long as the estimated probability of a pandemic remained >1 every 80 years.
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CEO of Professional Science Editing for Scientists @ prosciediting.com