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This approach might be too conservative, due to a high probability of correlation between the outcomes [ 65].
Fig. 1 shows the probability of correlation between two randomly chosen genes and that for known pairs with similar known gene/TF interactions.
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The probability of correlations for those sites affected by the waking potentiation (three electrodes in NREM and one in REM sleep showing significant changes in the PAS-25 vs. PAS-50 comparisons) points to a significant positive relation only for the Fp2 electrode (r = 0.72; p<0.72).
Herein, we combine the differential co-expression study with stochastic process model by using the solution of random walk model to approximate the condition probability of correlations.
The hypothesis is that pathways that are affected frequently by drugs causing the same ADR have higher probabilities of correlation with an ADR than pathways that are affected less frequently.
Open image in new window Fig. 6 Probability distribution of correlation coefficient R at the national and the regional scales for (a) chilling injury and b heat damage.
To define a cut-off value that ensured the exclusion of unreliable data in downstream analysis, we calculated the probability of positive correlation for each gene based on the distribution of the correlation coefficients.
Correlation analysis between the first principal component and the benthic data was then performed with the probability of each correlation coefficient corrected to account for temporal autocorrelation (Pyper & Peterman 1998).
The use of two evaluation methodologies provides different views on mobile broadband deployment models which are expected to increase the probability of good correlation with real-world deployment scenarios.
Further, a value of 40 60 bits for the unit of cost difference implies a 75 90% probability of the correlation between experimental and predicted activities.
Based on the nature of the data, only the probability of positive correlation between the genes in each pair is considered.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com