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The higher the score, the higher the probability of adherence.
Women treated with radiotherapy showed a higher probability of adherence (OR=1.8, 95% CI: 0.8 4.05).
The MOR in this study is defined as the median value of the odds ratio between a workplace (PHC) at the highest probability of adherence and a workplace at the lowest probability of adherence.
Finally, when compared with one-drug treatment, sequential oral endocrine therapy was associated with an increased probability of adherence.
An interesting finding is the fact that adjuvant chemotherapy was associated with a higher probability of adherence.
When workplace variance is high (empty model, item 4 MOR = 4.21, ICC = 41%%), the probability of adherence to guidelines varies remarkably (probability 0.1 0.8) between different workplaces.
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Furthermore, adjuvant chemotherapy (OR=2.14, 95% CI: 1.01 4.53) increased the probabilities of adherence to treatment.
CEACs broadly confirmed the neutrality of the cost and outcome findings, with probabilities of adherence therapy being the most cost-effective option ranging between 0.3 and 0.6 from both cost perspectives and for all outcomes for the willingness to pay thresholds we examined.
A 2005 meta-analysis focused on ARV programmes in resource-poor settings reported that, in fact, when medications were provided free-of-charge, there was a higher probability of achieving adherence and undetectable viral loads compared to situations where patients were required to pay for treatment [18].
In comparison, when workplace variance is non-significant and low (empty model, item 3, MOR = 1.74, ICC = 9 %), the probability of guideline adherence in different workplaces is more similar (probability around 0.5) (Fig. 1).
10 The probability of drug adherence (PDC>0.75) and its 95% CI was estimated as a function of the follow-up time, starting from the date of discharge of the index MI, using logistic regression models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com