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When the node is composed by a single protein, the probability of node activity is the probability of activation of this protein.
The probability of activity in any of these scenarios can be conceptually derived from the probability of activation of a protein.
Similarly, the conditional probability of activation of visible layer given the hidden state h is computed as begin{aligned} P v=1|h)=sigma (W^Th+a).
end{aligned} (3)The conditional probability of activation of hidden layer given the visible state v is computed as begin{aligned} P(h=1|v)=sigma (W^Tv+b), end{aligned} (4 where function (sigma ) is logistic function.
The probability of activation of the Src, Ras and PI3K pathways was statistically significantly different between different subtypes (Kruskal-Wallis p<0.001, p = 0.002, p = 0.021 respectively).
As ICa inactivates, the probability of activation of Ca2+ sparks diminishes, thereby allowing the SR Ca2+ ATPase and Na+-Ca2+ exchanger to return the [Ca2+]i to resting levels [13].
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The probabilities of activation of related faults between variants are likely to be greater for voters than for acceptance tests (ATs) (Arlat et al. [1988]; McAllister and Vouk [1996]).
In a recent quantitative meta-analysis of the neuroimaging literature on temporal processing, Wiener, Turkeltaub and Coslett [47] demonstrated that many so-called "timing" regions showed differential probabilities of activation depending on the type of timing task employed.
In other words, the method enables the estimation of the probabilities of activation of these cell functionalities.
We adjusted the probabilities of activation for proteins in our network in order to closely approximate the levels of BrdU incorporation in the absence of any treatment (control group).
The molecular interaction network topology is defined in the Cytoscape exported format and protein information as well as quantitative parameters can be defined in the node attributes file (e.g., protein name, probabilities of activation, and threshold).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com