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At each iteration we fit our robust model and compute the expected value of the posterior probability in favour of a single-exon heterozygous deletion call.
This analysis showed strong differences between Datasets 1 and 2. In Dataset 1, 300 reads mapping to an exon in the test sample were sufficient to provide complete power, whereas for Dataset 2, the posterior probability in favour of the deletion call could never exceed 30%, even with more than 500 reads.
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We propose that the likelihood ratio is qualified with additional robustness parameters to indicate the probability of misleading evidence in favour of the prosecution, under the assumption that a random man was a contributor instead of the suspect.
It has been proposed that not only should pretest probability not be discarded in favour of using calcium scoring but the combination of the two methods is a more powerful predictor of the need for further investigation and treatment.
Despite the very different application here from the original work, the proportions of correct model choices are in good agreement with Raftery, and differences in BIC between models of ≥6 are required to provide strong evidence (>95% probability of correct assignment) in favour of one or the other sub-model.
The probability of obtaining a LR<0.1 in favour of neutrality, is also almost 8% (Additional file 1; Figure S5).
In addition, the higher the probability of concordance, the lower the probability that a study's conclusions were in favour of vaccines' effectiveness (0.04, 0.02 to 0.09); table 2 shows examples of discordance between results and conclusions and take home message.
Kaplan-Meier analysis of cumulated survival probability showed a highly significant difference in favour of MARS.
In cases with retrospectively low probability for CD, GFD should be discontinued in favour of quality of life.
The authors used an oversimplified approach and, sometimes, questionable probability estimates, resulting in biasing their analysis in favour of the intervention (providing empiric anti- Candida therapy) and in favour of micafungin versus fluconazole.
Since the teacher had an interest in both didactic methods, the probability for her to affect the course arrangements in favour of one of them was regarded as small.
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