Exact(1)
Several interesting features can be noted from this figure: the spread-F occurrence probability decreases with a decrease in solar flux; the occurrence probabilities attain larger values from around September to March (spread-F season) of each year; and the onset time of this activity seems to start at around 1830 LT and continues until 0600 LT the following day.
Similar(58)
The EC50 value of capsaicin activation is in sub-micromolar range (Caterina et al., 1997; Yang et al., 2015), while the maximum channel open probability attained at saturating concentrations can reach close to unity (Yang et al., 2015; Cui et al., 2012; Hui et al., 2003).
At the preferred orientation (90°) the probability to attain large dendritic depolarization was 55%, and dropped almost linearly to a low probability of 1% at orientations further away than 45° from the preferred orientation.
Concerning temocillin, a 2-g TID dose given as intermittent 30-min infusion, provides a high probability to attain fT > MIC = 100% in ICU patients with normal renal function, provided the MIC is ≤ 4 mg/L.
The probability to attain remission or low disease activity was more than 75% for patients achieving low disease activity by the Simplified Disease Activity Index already after 3 months of treatment, while it amounted to only 25% for patients having high disease activity at that point in time [ 87].
In this formula, E is the expected value, pi are the probabilities of attaining each value, and ai are the attainable values.
Using these data in blood concentrations and MICs, the probabilities of attaining various percentages of the dosing interval during which drug concentrations remain above MIC (T > MIC) were calculated at several dosing regimens.
Using the pharmacokinetic model parameters, a Monte Carlo simulation was conducted to estimate the probabilities of attaining the bacteriostatic and bactericidal targets (40%and70%0% of the time above the minimum inhibitory concentration (T > MIC), respectively) in PF.
A Monte Carlo simulation using the pharmacokinetic model showed the probabilities of attaining the bactericidal exposure target (30% of the time above the minimum inhibitory concentration (T > MIC)) in PF were greater than or equal to those in plasma.
The cumulative probabilities of attaining viral suppression at month-6 and month-12 of ART were 71.8% (95% CI: 61.6-81.3) and 83.1% (95% CI: 73.8-90.5) respectively.
In our previous approach, Supervised Weighting for Composite Networks (SWC [ 8]), we integrated diverse data sources (including topological characteristics) with a supervised approach to accurately score edges with co-complex probabilities, and attained good performance in predicting large complexes (of size greater than three) in yeast and human.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com