Particular emphasis should be placed on pro-active screening and attempts to develop and validate tailored strategies for patients with cognitive or emotional dysfunction.
Other strategies such as pro-active screening and treatment and (focal) mass drug administration may have a larger impact in some settings.
This paper demonstrates the possibility of developing a pro-active network screening tool that estimates the crash rate using a stochastic cusp catastrophe model with the two-fluid model's parameters as inputs.
In the UK, port of entry tuberculosis x-ray screening of new arrivals has recently been dismantled, amid calls to strengthen primary-care-based screening programmes and to take a more pro-active approach to screening in this group [ 3, 7, 8].
Other screening approaches such as using general practise for pro-active and systematic screening have shown high testing rates in other studies [ 35, 36].
Nevertheless, the Boots study in London, which took place after the NCSP started, also found that pharmacists were not pro-active in offering screening but waited to be asked for a kit by clients [ 11].
Currently there are 14 active screens across the schools.
A pro-active primary prevention CV screening approach in general practice (GP) might be effective in a region with a low mean SES.
Pro-active GP based cardiovascular screening, supported by a GP laboratory, in a low SES-area could be well implemented and resulted in a high response rate of invited persons, and a high yield of newly detected persons with increased risk.
The importance of regular screening and pro-active management of cardiometabolic risk from childhood in TS cohorts is clear.
From a clinical perspective, this review highlights the importance of regular screening and pro-active management of cardiometabolic risk from childhood in TS cohorts and that future research should aim to address whether modification of these variables at a young age can alter the disease process and atherosclerotic outcomes in adulthood.
