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Pluralities like "the parts" have a privileged structure in terms of their individuals.
Herein, we further explore LA as a privileged structure for developing multimodal compounds to investigate AD.
In the constantly evolving world of drug discovery, there remains a constant: the privileged structure.
In this article, we define and review the concept of the privileged structure.
The indolin-2-one core is a privileged structure for antitumor agents, especially kinase inhibitors.
Chroman-4-one scaffold is a privileged structure in heterocyclic chemistry and drug discovery.
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Compounds from this privileged structure-based library were identified as antimitotic agents acting through destabilization of tubulin polymerization.
Privileged structure-based libraries have been shown to provide high affinity lead compounds for a variety of important biological targets.
One of these inhibitors, darunavir (TMC114), contains a privileged, structure-based designed high-affinity P2 ligand, 3(R),3a(S),6a(R -bis-tetrahydrofuranylurethane (bis-THF).
(3) "Privileged structures" theory suggests scaffolds often confer bioactivity.
New drugs introduced to the market every year represent privileged structures for particular biological targets.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com