Sentence examples for privileged organs from inspiring English sources

Introduction: The testes are immune privileged organs but they are subjected to acute and chronic inflammations that can impair spermatogenesis.

In vivo application of gene therapy is ideally suited to immune privileged organs such as the eye.

In immune privileged organs, Fas ligand has been shown to act via the induction of apoptosis on invading Fas-positive activated T cells and thus protects the cells from immune attack.

At 1 and 4 days post adenoviral injection, splenocytes were harvested and the cytokine profile in plasma and splenocyte culture supernatants was determined Short IL-18Rβ mRNA was highly expressed in tissue of lymphoid origin, and no expression could be observed in immune privileged organs like the testis, the eye and the brain, suggesting a prominent role in immune regulation.

Since 1873 the brain was classified as an "immune privileged" organ because it seemed to be not affecting by immune responses or inflammation.

Many of the earliest results were at first dismissed as inaccurate given the perception of the brain as an "immune privileged" organ, i.e. an organ that does not elicit inflammation in response to antigens or damage.

Tolerance to HuD suggests revisiting the model of the brain as an immune privileged organ.

This observation is surprising given the obvious decrease in brain iron content, a privileged organ that is affected last by iron deficiency [27].

The brain is considered to be an immune privileged organ, where BBB functions to prevent infiltration of immune cells from the blood [ 16- 18].

Primarily taken as an immune privileged organ, the brain parenchyma infiltration of peripheral leukocyte is tightly regulated at the level of the blood-brain barrier (BBB) [ 79, 80].

Although the brain is an immunologically privileged organ, lymphocytic infiltration into gliomas has been documented in large patient series (Brooks et al, 1978; Palma et al, 1978).