Sentence examples for prioritizing targets from inspiring English sources

And also the drug network is not very useful in prioritizing targets.

While model predictions require experimental validation, they are useful tools for prioritizing targets for experimental planning.

In this context, computational methods that integrate the knowledge of proteins and drug responses were utilized in prioritizing targets and designing drugs towards clinical trials with better efficacy.

Given the complexity of the signaling networks controlling systemic diseases such as cancer, computational models of cell signaling pathways are important tools for increasing understanding of pathological signaling and prioritizing targets to test experimentally [21].

By prioritizing targets using a layered approach, proteins that did not pass sequential cut-offs were filtered out [ 44].

Integrating complementary data from different sources is helpful for reducing noise and prioritizing targets (Gortzak-Uzan et al. 2008; Varambally et al. 2005).

Elaborating on accurate computational druggability prediction methods is a requirement for prioritizing target selection, designing new drugs and avoiding side effects.

Although phylogenetic footprinting aids in prioritizing target lists and increases specificity by ∼90% [31], it is important to bear in mind that it will miss conserved sites in regions that are not easily aligned.

As vaccine manufacturers scramble to produce new H1N1 vaccines for the upcoming influenza season, the limited global supply of the vaccine will require both prioritizing target groups for vaccination and exploring other interventions that can help reduce H1N1/09 virus transmission and disease severity, including the administration of antiviral agents (http://h1n1.nejm.org/).

Hence, there is an urgent need for general guidance on TB ACF, particularly on prioritizing target groups and selecting diagnostic strategies [ 2].

The fact that several of the genes in this list have been demonstrated, through experimental studies reported in the literature, to be important in rod photoreceptor function provides support for the utility of this approach in prioritizing experimental targets for further experimental investigation.