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Here, in designing siRNAs to treat Huntington's disease (HD), a dominant neurodegenerative disorder, we prioritized selection of sequences with minimal off-targeting potentials (i.e., those with a scarcity of seed complements within all known human 3′-UTRs).
In[18], a prioritized selection (PS -based IC scheme is develoPS -based
For comparison, two relevant coordinated beamforming schemes, i.e., the prioritized selection (PS -based IC scheme (PS -based[18] and the joICt schemeion-based interference coordination scheme (JS-IC) in[20] are simulated, too.
Such a prioritized selection samples the feature space incompletely.
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In silico predictive models permit inexpensive, rapid "virtual screening" to prioritize selection of compounds for experimental testing.
[27] discussed the combination of QFD with analytic hierarchy process analytic network process (AHP ANP) and DEAHP DEANP methodologies to prioritize selection criteria in a service context.
These results indicate that prioritizing selection of positions by high degree rather than by high MI may be more useful for identifying the ligand-binding cavity of GPCRs.
Each of these parameters can be assessed and used to prioritize selection of a candidate drug or class of drugs for CPMC PhAESIS evaluation.
This necessitates developing methods to prioritize selection of the molecules such that measuring their activity would be most informative for understanding the crosstalk.
We wished to use comparative genome analysis to help prioritize selection of possible gene or protein targets for developing novel control technologies, which could include vaccines or design of novel inhibitors aimed at selected gene products.
The system is being designed to enable analysis of spatial patterns in contaminated sediments and help prioritize selection of additional sampling sites, as well as to provide relevant information for risk assessment, risk communication, and remediation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com