GO has also been heavily utilized as a data source for various candidate disease gene prioritization applications.
Indeed, gene expression data are a crucial constituent of several web-based gene prioritization applications; however, it tends to be used in concert with other data types, such as pathway/interaction networks or functional annotations.
GeneTIER replaces knowledge-based inference traditionally used in candidate disease gene prioritization applications with experimental data from tissue-specific gene expression datasets and thus largely overcomes the bias toward the better characterized genes/diseases that commonly afflict other methods.
Other positive selection measures that report values for contiguous blocks of gene sequence are highly useful in gene-prioritization applications[ 33]; however, they are generally unsuited for the challenge addressed here, which is to prioritize variants within genes, and would be expected to have severe convergence issues, so they were not considered.
Recently, Dr. Resch provided technical expertise and analysis to Global Fund in support of their effort to develop new policies for country eligibility, counterpart financing, and (application) prioritization.
The OMC-MAC addressed QoS provisioning problem for DCRN using user application prioritization.
To provide spatial products for application in prioritization of management, we developed spatially explicit estimates of occurrence separately for encamped and traveling modes.
The application of prioritization frameworks generally involves multiple services across many planning units and priorities for different services are not necessarily congruent.
With the blooming of hydrogeosciences, hydropedology is a timely addition in this era of interdisciplinary, multidisciplinary, and systems approaches for developing comprehensive prioritization of science and applications in Earth science.
The River Styles framework (Brierley & Fryirs, 2000, 2005, p. 398) is a geomorphic tool that feeds scientific information into river management applications and prioritization, striving to ensure that actions reflect the values of a given place.
