Sentence examples for prioritising candidate from inspiring English sources

Prioritising candidate genes for further experimental characterisation is a non-trivial challenge in drug discovery and biomedical research in general.

The identification of genes with at least putative roles in ovarian cancer validates our approach of a multi-in silico analysis approach for prioritising candidate genes for ovarian tumorigenesis.

However, the assay should capture genes involved in the fundamentals of cellular prion infection, propagation and clearance thus providing triage for prioritising candidate genes for future studies.

For prioritising candidate genes within the Salmonella shedding associated modules that could possibly determine better immune responses to Salmonella challenge, we restricted further analysis to the pink and grey60 modules.

The analysis report classifies variation by classes to help the user in prioritising candidate mutants.

Instead, it should be used as a guide to prioritising candidate variants to take forward for follow-up analysis.

We began by prioritising candidates with respect to growth rate from the miRNA, mRNA and proteomic datasets in isolation.

Previous attempts to prioritise candidate regulators in silico have involved the correlation of the expression levels of the genes comprising the trans-eQTL cluster with those of candidate regulators co-localising with the cluster locus [18].

Correlation-based methods have been applied to prioritise candidate genes or to infer co-expression networks, but in many cases genotype information is not utilised in the analysis [23], [24].

Tools to help prioritise candidate isoforms for testing are largely absent.

The goal of our study was to use the functional information to prioritise candidate disease genes.