Sentence examples for prior to the manifestation of from inspiring English sources
With the advent of molecular imaging, it will be possible to detect these changes prior to the manifestation of disease.
This coincides with a significant decrease of mucosal ion transport but not of barrier permeability in young animals prior to the manifestation of the disease.
During the acute hypoxic challenge, we propose that pathologic alterations associated with changes in calcium handling cause the emergence of irregular contractions prior to the manifestation of systolic pump failure attributable to MHC isoform switching.
Intriguingly, this study showed reproducible perturbations that occurred in core networks that could be monitored prior to the manifestation of disease symptoms.
The gene expression defects were apparent in the organogenic region of shoot apices just prior to the manifestation of the morphological defect.
In neurodegenerative disease, progressive degenerative changes can be detected many years prior to the manifestation of clinical symptoms including cognitive and motor deficits.
This increase of PCT prior to the clinical manifestation of infection is an important finding of our study and parallels results from Schuetz et al. [ 22].
20 Importantly, young people often exhibit substantial levels of disability prior to the complete manifestation of a mental disorder, reflecting either the putative prodrome of an illness 21 22 or the consequence of disengagement from employment and education.
Previous studies have reported that hyperglycemia-induced increase in oxidative stress was directly implicated in endothelial dysfunction and identified as an early pathological event of diabetes prior to the overt manifestation of symptoms [ 1– 3].
The levels of HBP were elevated up to 12 h prior to the clinical manifestation of septic shock [ 5].
Our study, which is the first to assess maternal PWV prior to the clinical manifestation of PE, is also consistent with the above findings.
