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However, the mean ages of the subjects in the different groups were comparable, and dietary influence was minimized by collecting samples in the early mornings prior to the intake of food.
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9 Motor fluctuations generally initially present as a re-emergence of PD symptoms at the end of a given dose, prior to the scheduled intake of the next dose often referred to as end of dose wearing off.
Prior to the investigation intake of caffeine or alcohol was not allowed.
A validated Block food frequency questionnaire (Block et al. 1986, 1990) was self-completed by 98% of case and control participants and assessed typical dietary intake during the year prior to the interview, including intake of fruits, fruit juices, and vegetables (Gaudet et al. 2004).
At intake, 14 persons were known to have been released from treatment for leprosy prior to the study intake.
Finally, it is possible that the biomarker samples were drawn outside the time period relevant for cancer development, as phytoestrogen intake prior to the maturation of the mammary gland may exert the greatest influence over breast cancer risk [ 35].
Due to the presumed date of infection prior to intake of the investigational product (prophylactic effect not assessable), these episodes were not considered in the analysis.
Reduced water intake in these animals prior to the induction of sepsis may have contributed to hypovolaemia, decreasing cardiac output.
Participants were asked to fast for at least 12 h and abstain from alcohol intake for 24 h prior to the administration of the DM-BT.
An intake visit was scheduled prior to the start of the program to review details of the program and to perform an initial study assessment (as described below) and a physical examination.
Only oral granisetron was given 1 h prior to intake of the chemotherapy to prevent nausea and vomiting.
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