Sentence examples for prior to the approval of from inspiring English sources

2 Prior to the approval of ospemifene, the only FDA-approved treatments for dyspareunia contained estrogen, which when taken orally has been associated with an increased risk of breast cancer 3 and other potentially serious complications 4– 6 in large clinical trials of hormone replacement therapy.

Prior to the approval of fidaxomicin, oral vancomycin was the only agent approved by the US Food and Drug Administration FDAA) for the treatment of antibiotic-associated pseudomembranous colitis produced by C. difficile.

These results should be considered in environmental impact studies prior to the approval of new dams.

Prior to the approval of any renewal of permit the regulatory authority shall provide notice to the appropriate public authorities.

So are you going to require studies like that, either in children or in adults, prior to the approval of a drug?

The delay of the regulatory review process prior to the approval of AquAdvantage was perceived by many as sort of a dead end in the United States for this technology.

Enrollment began in February 2002 and was closed in September 2003, prior to the approval and clinical use of drug-eluting stents (DES) in the United States.

Prior to the recent approval of the first of Gilead's new drugs, standard treatments cured about 75percentt of patients and required either 24 or 48 weeks of therapy.

12 Prior to the US Food and Drug Administration FDAapprovalval of lorcaserin and phentermine/topiramate extended release (ER), the only FDA-approved long-term obesity pharmacotherapy was orlistat; the latter remains the only long-term therapy approved in Europe.

Prior to the FDA approval of the first genetically engineered crop, researchers at the FDA found that GMOs posed no risk to humans, and emphasized the minimal dangers to environment.

A cost-benefit analysis shall not be required under subparagraph (A) prior to the initial approval of a written agreement for a matching program that is specifically required by statute.