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In prior times, when the major choices about vocation, family and community location were settled by age 20 or so, there was less room for agonizing about what to do in life than exists in our time, in which many young people are still searching at age 30 or later.
As a corollary, these data suggest that any mRNA transcripts required for MCM, Cdc45, or PCNA protein translation, or for other factors involved in the loading of these proteins onto chromatin, would likely have been made at sufficient levels prior to time when cells lose their requirement for new mRNA production and begin MCM loading.
It's actually something you have to train yourself to do, to say "before" instead of "prior to". But as you say, people will say five words– "prior to the time when"– as opposed to "before". And in a way, plain English is no one's mother tongue.
Remindings prompted learners to practice retrieval of a prior episode at a time when the prior episode could be recalled, re-exposed learners to the earlier episode, and supported long-term retention of that information.
Points (1) and (2) demonstrate that in Fz3 -/- embryos, axon stalling and precocious motor neuron death occur two days prior to the arrival of WT motor axons at their final targets and two days prior to the time when trophic support from distal/final targets is needed to maintain WT motor neuron viability.
However, householder data for all but the 2008 gardening season were collected prior to the time when residential users were subject to penalties under the bylaw, and much of the observed change occurred prior to that season.
The sodium chloride crystallizes and precipitates out prior to the time when the other dissolved constituents become concentrated to saturation.
In addition, it extends the standard model's notion of transaction time by permitting data to be physically added to a table prior to the time when that data will appear in the table as production data, available for use.
And one of the examples you have in the book is if you're ever tempted to write, "prior to the time when" just change it to the word "before". And you had lots of great examples like that.
However, Brunson's earliest days -- we're talking a decade prior to the time when ClickFunnels even had become a thought in his mind -- were wrought with difficulties.
Freud himself thinks that this feeling (which he cannot find in himself) is probably a vestige of infantile consciousness prior to the time when the infant begins to distinguish himself from his human and non-human environment; and he thinks that the oceanic feeling does not involve a strong enough need to be the source of all religious energy.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com