Survival was better in patients with the following characteristics: nonsurgical initial neck treatment, negative initial disease resection margins, no history of prior recurrence, ipsilateral location of the ICR-PTN relative to the primary, and use of surgical salvage.
The most useful prognostic parameters are tumor grade, stage, size, prior recurrence rate and the synchronous presence of CIS [3].
primary or recurrence, prior recurrence rate, use of intravesical therapy.
number of tumors; tumor size; prior recurrence rate; T category; presence of concurrent CIS; tumor grade.
Recall patients were excluded if a prior recurrence had been documented and successfully treated.
Prognostic factors are based on clinical findings: primary or recurrence, prior recurrence rate, use of intravesical therapy.
No association was found for other characteristics, such as gender, tumour stage, grade or size, CIS presence and prior recurrence.
(Here the RFS estimate treats deaths without prior recurrence as censored, because the model is intended to infer the relationship between underlying tumour biology and clinical tumour behaviour).
Unfortunately, the recurrence and progression of the disease may not be well predicted in individual patient using the clinical and pathological parameters including tumor size, grade, stage, the multiplicity of lesions, and prior recurrence rate [ 1].
A simple scoring system was derived based on six clinical and pathological factors (number of tumors, tumor size, prior recurrence rate, T stage, presence of concomitant CIS, and tumor grade).
