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Independent of the radionuclide used, the response rate is reported to be in the range of 30 40% for partial remissions and stable disease in prior progressive patients has been reported in ∼40 50% [ 62– 62].
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14, 26 Increased expression of PlGF in particular was observed prior to progressive disease in patients receiving bevacizumab and chemotherapy.
GOG-132 is the only trial to report substantial crossover to taxanes in the control arm prior to progressive disease being reported; OV10 reported 4% and ICON3 3% of control patients receiving taxane-based treatment at this time.
The clinical dilemma is that many women are inadvertently admitted prior to progressive labor (i.e., pre-active labor) yet held to dilation rate expectations of active labor [ 4].
Patients dying prior to documented progressive disease were considered to have experienced progressive disease at death.
Total relapses prior to secondary progressive and number of relapses from Year 3 to secondary progressive exerted no detectable independent effect on the attainment of hard disability endpoints from DSS 3 upward.
This independent nucleation is a necessary step prior to the progressive development of a definite fibre texture in thicker deposits.
In persons with prior paralytic poliomyelitis, progressive muscle weakness can occur after a stable period of at least 15 years.
30 minutes prior to a progressive ratio (PR) test.
To stabilize HIF-1α cells have been pre- treated for 12 hr with cobalt chloride (CoCl2, 100 µM, Sigma) prior to starting progressive high oxygen exposure and/or time course treatment with BMP2 the day after.
Treatment courses were repeated every 4 weeks × 6 unless prior evidence of progressive disease.
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