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Although rank-based methods have been suggested [32], [33], the important conceptual advantage of threshold-freedom lies in considering gene expression data simultaneously, without the uncertainty associated with prior gene list extraction [26].
Repeated single nucleotide extension to a prior gene region is performed to determine the boundaries.
EXPRSS also identified expression in regions of the genome without prior gene annotation.
In addition, there were 46 prior gene interactions available for us [ 7].
Assume a protein-encoding gene, and the coding region G represents the prior gene region.
Type II: duplicated gene inserted at a locus where no prior gene existed.
Similar(39)
This explanation is supported by prior gene-specific studies.
Prior gene-targeting studies have suggested, however, that CR2 expression may be needed to maintain tolerance.
Without any prior genes of interest, it may be better to validate experiments with the highest-ranked genes, such as top-ranked HEART3.
We confirm and augment prior risk gene and gene set enrichment results for SCZ and NDDs.
To avoid prior bias, gene duplication/loss, gene fusion/fission, and speciation were assigned an equal cost of 1.
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