Sentence examples for prior dose from inspiring English sources

They'd also added, at a minimum, an extra two weeks between cycles so that patients would have fully recovered from the toxic effects of the prior dose before they got the next.

Prior dose to the spinal cord and lung were taken into account before designing the radiation treatment plan.

In addition, increasing the lipid dose in a prior dose of mPEG2000-liposomes (0–25 μmol/kg) increased the induction of the phenomenon in a sigmoid manner.

Herein, we report on a study of issue of whether physicochemical properties of a prior dose of liposomes such as degree of PEGylation, PEG chain length, lipid dose, surface charge, size, play a role in inducing this phenomenon.

The results reported here clearly indicate that the physicochemical properties of a prior dose of liposomes strongly affect the pharmacokinetic behavior of a subsequent injection of mPEG2000-liposomes: Thextentnt of PEGylation and the lipid dose had an effect, but the surface charge and size did not.

Women who were temporary residents, had had a prior dose of SP-IPTp, had a haemoglobin concentration <5 g/dl, gave a history of sensitivity to SP, amodiaquine or an artemisinin, had an illness requiring hospital admission or declined to join the trial were excluded (Figure 1).

This led us to assume that prior dosing with liposomes might enhance the intra-tumoral accumulation of a subsequent dose, and hence improve the therapeutic efficacy of entrapped l-OHP.

A dose of 0.15 mg/kg was chosen after prior dose-finding studies, which ruled out significant effects of capadenoson on blood pressure between 0.1 mg/kg and 0.3 mg/kg, whereas there was a significant reduction in resting blood pressure at higher doses (Fig. S1).

Prior dose-finding pilot experiments determined this dose to result in good cell viability and reproducible NK cell activation (data not shown).

Also, the lower dose (8 μg) was chosen based on prior dose-ranging studies and may reflect the fact that patients with IBS often respond to medications at lower doses than other patients.

The concentration of IGF1 (50 ng/ml; Peprotech) was determined by a prior dose-response experiment and was somewhat similar to that used previously in fibroblasts and other cells (Chetty et al., 2006; Izumi et al., 2006; Yin et al., 2009).