Sentence examples for prior agents from inspiring English sources

Thus, only 14.2% of the patients met the guideline criteria for the use of prior agents and appropriate monitoring.

Thus, patients have a similar chance of survival after the last treatment with either O or I, irrespective of prior treatment sequence or number of prior agents.

DURATION-1 [ 31] and DURATION-5 [ 29] examined the effects of these two agents on patients who were achieving suboptimal control on diet and exercise alone ± metformin, a sulfonylurea, a thiazolidinedione, or a combination of the prior agents.

33 45 50 46 44 When TNFi preceded TCZ therapy, requirements for time of discontinuation were different among prior agents: for etanercept it was at least 2 weeks, while for adalimumab and infliximab at least 8 weeks.

Everolimus may be used after axitinib, in view of the fact that the RECORD-1 trial also enrolled patients who had received two targeted therapies, and that the number of prior agents employed was not predictive of PFS.

The preliminary results from a non-randomized phase II trial that evaluated ponatinib at a dose of 45 mg/day in heavily treated GIST patients (74 % had ≥4 prior agents) the clinical benefit rate (CR, PR, or SD ≥16 weeks) was 55 % in patients with primary KIT exon 11 mutation, but responses were also observed with the 30-mg dose [ 30, 52].

We explore this question by comparing the degree to which an upcoming sentential theme is anticipated by combining information from a prior agent and action.

In patients failing one prior agent, an ORR of 42% was found, in contrast to 18% in patients failing more than one targeted treatment.

A majority of the 180 anti-TNF-experienced patients had received ≥2 such agents and >70% had discontinued prior agent(s) due to lack of efficacy/intolerance (table S1).

Three-quarters of the patients had received two prior endocrine agents, and 22% had received three prior endocrine agents.

Prior investigational agents were discontinued at least one month before treatment.