Sentence examples for prion of from inspiring English sources
[URE3] is a prion of Ure2p, a regulator of nitrogen catabolism, while [PSI +] is a prion of Sup35p, a subunit of the translation termination factor Sup35p.
The beneficial [Het-s] prion of Podospora anserina poses an important contrast in its structure, biology, and evolution to the yeast prions characterized thus far.
For instance, the well-characterized [PSI+] prion of Saccharomyces cerevisiae does not propagate in Δhsp104 cells or in cells overexpressing Hsp104.
Ure2 is the protein determinant of the epigenetic factor [URE3] of Saccharomyces cerevisiae, which has been demonstrated to represent a prion of yeast [14], [15].
Reviewer #2: The manuscript submitted by Hochschild and colleagues addresses the ability of E. coli to support propagation of the [PSI+] prion of yeast through the self-assembly and inheritance of aggregates of the prion-determining domain (NM) of the Sup35 protein.
Classical scrapie (subsequently referred to as scrapie) and Bovine Spongiform Encephalopathy (BSE) are transmissible spongiform encephalopathies (TSEs), a group of fatal neurodegenerative disorders of animals and man which are characterised by the deposition of a misfolded isoform (PrPSc or prion) of a cellular protein (PrPC), spongiosis and gliosis.
Pathophysiology of prion colonization of lymphoid organs has been studied intensively, yet how myositis influences prion accumulation in muscle is unknown.
But a new variant of C.J.D. now is killing young Britons who acquired the disease from eating cattle infected with abnormal prions of their own.
She concedes, however, that genetically engineered prions of the type produced by the Lindquist team might help resolve the debate over the prion-only hypothesis in mammals.
The latter group included nine males and 11 females, already genetically sexed as above, and 20 prions of unknown sex.
Yet, for the time being, prions of transmissible spongiform encephalopathies seem to remain unique pathogens.
