The summer of 2012 has poignantly proved my point: Virtually every major story, from the Olympics, to college sports, to professional leagues has been shaped by legal principles studied in the first year of law school -- civil procedure, constitutional law, contracts, criminal law, and business law.
These preclinical results, obtained after coinjection of [111In-DOTA]MG11 withethe NEP inhibitor PA, warrant further validation in a "proof-of-principle" study in patients.
The above promising results have prompted further research toward clinical translation of the proposed concept in a first "proof-of-principle" study in man, using [111In-DOTA]MG11 as a paradigm.
This is to say that they may all be decided in the 'in principle' sense studied in computability theory – i.e. by an effective procedure which halts in finitely many steps for all inputs.
I remember more about the professor's fish necktie than I do the principles that I studied in that Intro to Economics class my junior year in college.
Many generalizations in various different directions of maximal element principle have been studied in the past; for example, see [2, 3, 6 10] and references therein.
In people with dementia, EL principles have mostly been studied in laboratory tasks that have little practical relevance for the participants concerned, yet show positive effects.
Proof-of-principle studies in tissue engineering have strongly demonstrated the potential of engineered functional organs such as heart, liver and kidney[66 68].
However, compared with PA, TO and its prodrug Race induced less potent increases of tumor uptake, highlighting the significance of inhibitor type, administration route, and dose for implementing a first proof-of-principle study in human.
This proof of principle study in experimental rats indicates that the etiology of meningitis can potentially be established rapidly without prior culture of the infection-causing microorganism using a very small amount of CSF.
Various other single-cell functional genomic modalities have also been reported, primarily as proof-of-principle studies in cell lines.
