Sentence examples for principles of replacement from inspiring English sources
The use of animals in Yale research must be approved and conducted in support of the principles of replacement, reduction and refinement, and in accordance with federal regulations and University policies and procedures.
From this standpoint, the universally advocated principles of replacement, reduction and refinement aim to address the ethical conflicts arising from the assumed inability of individual animals to consent to potentially harmful procedures, but such principles in fact reflect a lack of individual centrality.
In the use and care of the mice, we followed the humane research principles of replacement, reduction and refinement endorsed by the National Health and Medical Research Council of Australia.
Finally, in keeping with the ethical principles of Replacement, Reduction and Refinement with relation to the use of non-human primates in medical research, experiments were only repeated until statistically meaningful results were observed.
This model was further optimized keeping in mind the three Rs' principles of replacement, reduction, and refinement [ 38].
It complies also with internationally established principles of replacement, reduction, and refinement in accordance with Guide for the Care and Use of Laboratory animals (NRC, 2011).
Current animal ethics requirements emphasise the principle of replacement, refinement, and reduction (3Rs) in research using animals based on established guidelines [ 154].
The 3Rs principle of replacement, reduction and refinement has become widely accepted, and is incorporated into the legislation governing the use of animals in several EU member states and throughout the world.
It has become widely accepted that whenever animals are used in scientific procedures, the 3Rs principle of replacement, reduction and refinement described by William Russell and Rex Burch should be adhered to.
Guided by the principles of bioisosteric replacement and pharmacophoric fragment migration, a series of novel quinoxalinone derivates were designed, synthesized and evaluated for their VEGFR-2 inhibitory potencies.
The principle of growing replacement tissue cells from embryonic stem cells was endorsed at the hearing by Dr. Harold Varmus, director of the National Institutes of Health.
