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In the substrate molecule, the hydroxyl group of T288 is in principle capable of reaching the γ-phosphate of AMPPCP bound to the enzyme monomer as shown by TMD simulations.
Here's one principle for reaching that goal: an ethics of citizenship should itself reflect the diversity of the citizenship.
Multicell joint processing has originated from information-theoretic principles as a means of reaching the fundamental capacity limits of cellular networks.
Amid clamoring from his more conservative members, Mr. Boehner eventually reaffirmed his own conservative principles, abandoning even the pretense of reaching a bipartisan solution on the spending cuts.
The Israeli prime minister has floated the idea of reaching a joint "declaration of principles" with the Palestinians, an idea that Mr. Abbas endorsed.
President Bush's masterly way of reaching out to Muslims at home and abroad has displayed before the world our principles of tolerance.
The principle of consumption reached its peak in the 1920s (Cross 2002) paralleling the burgeoning success of Nelly Don's Donnelly Garment Company.
"This Court's cases have expressed constitutional principles of broader reach.
The other, a statement of principles reached last fall, appeared to evaporate before the ink dried.
They resumed in July, with a broad agreement on the principles of the transaction reached by the end of that month.
These topological phases are a manifestation of some new principles, with far reaching consequences.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com