In conclusion, this pilot Phase I study of safety, feasibility and dose finding of intradermal rdESAT-6 provides proof of principle of a specific skin test for human use.
Although the test data set did not reflect biological activity occurring in all areas of the DACS Network, it enabled a detailed proof-of-principle evaluation of a specific portion of the network (ie, relevant senescence sub-models) as a means to ensure that the nodes and edges placed into the network through manual curation provided an accurate reflection of currently known biology.
Trade agreements can't stand in the way. 5. "In conclusion, a clear signal from the U.S. at this stage that it is accepting the principle of negotiating a specific chapter including provisions on unrestricted access to U.S. natural resources would show our resolve while further encouraging investments in the upstream and downstream energy sectors".
We discuss in the second part about the principles of determination of a specific mechanical design process.
That is, the social practice of dealing with the principles in a specific way in biomedical ethics (e.g., as instruments to teach ethics to students and health professionals) may at least to some degree foster or erode the foundation of the principles in common morality.
The work focuses on the principles for the design of a specific static hood and on the definition of an optimal sampling procedure for the assessment of landfill gas (LFG) surface emissions.
In well-mixed reaction systems the systematic investigation of molecular reaction mechanisms has led to considerable insights into the design principles for the generation of a specific type of dynamic behavior such as bistability or oscillations [ 14, 15, 64].
This chapter outlines the approach through a set of principles, wherein each principle focuses on systematic achievement of a specific quality engineering concern and contributes to the quality assurance of software systems in a consistent manner.
Since the French radicals believed that the principles of reason mandate a specific kind of constitution, and since traditional French institutions were very far from that ideal, they held that these institutions are contrary to reason, so that it was obligatory to abolish them.
(Foray, 2015, p. 3) argues for smart specialization as a principle of the prioritisation of a specific technology or industry: The main goal of a smart specialisation policy is to concentrate resources on the development of those activities that are likely to effectively transform the existing economic structures through R&D and innovation (emphasis in the original).
