Sentence examples for principles in gene from inspiring English sources

The presence of biologically meaningful covariation in a setting with no experimental perturbation underscores the need for replication and careful adherence to statistical design principles in gene expression studies.

Our results strengthen the hypothesis that the special network topologies that are necessary for network-dosage compensation may be recurrent network motifs in eukaryotic genomes and therefore may be an important design principle in gene network assembly in cells.

This principle of hierarchy in gene number, diversity, and phenotypic effect is the foundation upon which the theory and methodology for detecting genetic networks underlying complex phenotypes can be developed.

In principle, the observed differences in gene expression between human and mouse transcripts in fused cells could be due to at least three possibilities.

As a proof of principle, we report changes in gene expression generated by this microarray in three independent experimental set ups.

DOI: http://dx.doi.org/10.7554/eLife.00603.023 Here, we used comparative functional genomics of transcriptional profiles measured during growth of 15 species of Ascomycota on glucose to identify several principles in the evolution of gene expression in a complex phylogeny.

As proof of principle, we have reported changes in gene expression generated by this microarray in two independent experiments.

The nematode Caenorhabditis elegans is an important model for studying principles of gene regulation in multi-cellular organisms.

Yeast is one of the less-complex eukaryotes, but the emergence of evolutionary principles for gene regulation in these experiments represents another addition to the list of unanticipated outcomes of genomic biology.

In principle, gene drive could give an endangered species a boost, wreck the genetic defenses that allow some weeds to resist herbicides, or drive a disease-carrying mosquito to extinction.

In principle, gene families are extended by three major mechanisms: segmental duplication, tandem duplication and retroposition [ 45, 46].