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But even basic principles are problematic.
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It is assumed that conditional hazards are constant within a single reporting interval (e.g. one year), which will in principle be problematic for conditions with high initial case-fatality, for example heart attack (or stroke).
The general principles that provide a basis for the empiricist view, e.g. Hume's overall account of our ideas, the Verification Principle of Meaning, are problematic in their own right.
"Taxes that are primarily directed at foreign companies are problematic in principle in the European internal market," he told the Munich newspaper Süddeutsche Zeitung.
Such differences are problematic in that the conservation of mass principle is violated.
JAMES SUROWIECKI: In principle, it's not clear to me why periodic audits of the Fed's past performance are problematic.
These interventions are problematic.
Both claims are problematic.
All are problematic.
Toilets, while practical, are problematic.
"Oaks are problematic," Barnard said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com