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The treatment principles applied in this study follow the evidence-based guidelines for the treatment of CLBP, developed in Europe (http://www.backpaineurope.org)[ 27].
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The system was developed essentially for FHR analysis, but the same principles were applied in this study for analysis of the MRH, after scale conversion [ 13].
The intention-to-treat principle was applied in this study.
The principles applied in the current study could be extended to incorporate rare SNPs or copy number variants, or regulatory SNPs remote from genes using denser new generation GWAS platforms.
For the online condition, the CBT treatment manual for depression [ 29] was adapted for use as an internet-based intervention, based on the principles applied in a number of previous studies [ 3, 41- 43].
The transmission-type phase-contrast DHM applied in this study is based on the principle of the Mach-Zehnder interferometer.
The same principles apply in low-income settings: one study from Tanzania has shown that simple triage using vital signs can predict which patients have a high risk of mortality [ 41].
Similar principles apply in politics.
As shown in Figure 2, Langmuir's adsorption principle is applied in this isocratic elution system.
MCDA principles were applied in the present study to define criteria regrouping terms referring to the same concept and to categorize criteria into a meaningful and intuitive architecture (clustering).
This principle applies in nearly every industry.
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