These mutants represent proof-of-principle of the suitability of the screen in finding signaling components between ligand recognition and calcium flux.
The present results thus suggest that mucosal delivery of anti-inflammatory IL-1ra produced by recombinant S. gordonii can reduce disease severity in the IL-2-/ IBD-like pathology, representing the "proof-of-principle" of the suitability of S. gordonii for mucosal delivery of therapeutic proteins.
This study provides proof of principle for the suitability of the TNT/Ti wire implants for localized bone therapy, which can be customized to cater for specific therapeutic requirements.
Proof-of-principle for the suitability of the GRAS data collection for PGAS has already been demonstrated [[ 11], and Grube et al: Calcium-activated potassium channels as regulators of cognitive performance in schizophrenia, submitted].
Both basal features of the residual-QSAR principle of self-consistency and suitability for non-congeneric molecules make it appropriate for conceptually assessing the mechanistic description of genotoxic carcinogenesis.
Based on the principle of "objective and object suitability", the socio-scientific research allows us to make a rough distinction between variable-manipulative and variable-configurative strategies as illustrated by the diagram below (see Fig. 1, modelled on Schaffer [4]).
Journal of Biology will also bring to the fusion its policy (already shared in part with BMC Biology) of taking advice from Editorial Board members on the suitability in principle of submitted papers for the journal before sending them to referees, so that referees are asked to judge only the technical soundness of the paper, and not its level of interest.
MaxEnt is a model based on the principle of maximum entropy that predicts continuous habitat suitability maps of potential species occurrence under a set of selected environmental variables.
Here are two pianists bringing with them separate questions of suitability, and maybe answers to both.
Each candidate also emphasizes the issue of suitability for the job.
