The improvement of healthy lifestyles through modification of eating habits, daily physical activity practice and avoiding sedentary behaviour are the principle modifications that can prevent or reduce the risk of obesity [ 9]. Specific recommendations based on expert opinion or supported by clinical studies are proposed [ 10].
Recently, we reported on a proof-of-principle modification of an electron transfer dissociation-enabled quadrupole linear ion trap (QLT -Orbitrap for GC/MS to assess the merits of the Orbitrap as a detector for GC.
PTs' responses had more emphasis on the use of therapy assistants, application of manual handling skills and ergonomic principles, modification of treatment techniques and avoidance of particular activities or tasks.
When an initiation event occurs, in principle, the modification that is outnumbered is able to overtake the opposite modification but the probability of this event is relatively low.
Based on the colloidal system equilibrium and the lowest energy principle, the modification mechanism of the HMABs modified by PRS and PRM was analyzed in this paper by using the effects of swelling and interface layer.
In CE, the cation sublattice is partially or completely replaced by a sublattice of new types of cations, with (in principle) minor modification of the anion sublattice.
In principle histone modification enzymes can be targeted to chromatin either directly through interaction with components of chromatin and/or indirectly through interaction with transcription factors or secondary regulatory proteins.
Should strong evidence emerge for the irrelevance of one of the principles, a modification might be considered.
In principle, epigenetic modifications are heritable changes that influence gene expression without altering the primary sequence of DNA [ 11].
Remarkably, C1a-genes are bistable, that is, the associated nucleosomes can in principle regain histone modification in course of stochastic modification reactions (see: Fig. S1).
We conclude that a principle phenotypical alteration upon mild modifications of Rho pathway activity is a change of the chirality index, or, in other words, mild modifications of Rho pathway activity change active torque generation without affecting active tension.
