Sentence examples for principle in the development from inspiring English sources

These management consequences and possible solutions for the implementation of the sustainability principle in the development of the territory as civil and economically independent one, aimed at achieving non-destructive long-lasting anthropogenic transformations in coastal environments, were paid special attention.

In principle, with this conformation, replacement of the polar carboxyl group by a small hydrophobic substituent might enhance the affinity and PDE4-inhibitory potency of the compound, and we have previously used precisely this design principle in the development of another PDE4 inhibitor series [49].

This sort of multi-faceted approach has been the guiding principle in the development of the SAIL databank to date, whilst recognising the need to continue incorporating further improvements with the rapid developments in the field of health informatics, and to retain the flexibility to respond to possible political changes and new legislation and regulations.

"One of the key principles in the development of the internet has always been the concept of running code," explains Mr Twomey.

Validation and verification are two main principles in the development of a system.

The utilization of biopharmaceutical and pharmacokinetic principles in the development of veterinary controlled release drug delivery systems is essential for a rationally designed product.

This serves as a proof-of-principle in the development of genetically clean gene therapy approaches to cure this monogenic inherited disease.

Similarly, a systematic review of online weight management programs underlined the importance of recreating the human experience and of providing a supportive experience as key principles in the development of web-based programming [ 42].

A precise understanding of the cellular mechanisms associated with Wolff's law and osseous tissue transformation, may synergize with biomechanical principles in the development of appropriate and effective treatments for people with difficult fractures.

Assessment of disease modification therefore remains a principle challenge in the development of new therapies for ankylosing spondylitis.

Growth-associated butanol production would in principle enable the development of continuous or continuous-like processes, which are difficult to develop with the well-known solventogens like Cac and Cbe due to the well-known degeneration phenotype [ 31, 36].