Our attempts to introduce the system into transgenic mice gave proof of principle functionality and future directives for improvements.
However, prediction of resistance determinants by sequence similarity based methods clearly leads to an overestimation of resistance determinants since in principle functionality of these determinants remains unclear.
In sum, these data not only confirmed the high affinity of l αhCD70 for cells expressing CD70 but also demonstrated the principle functionality of the corresponding scFv upon TNC-driven trimerization.
The work-in-progress paper presents design principles, functionalities and structure of the facility, and outlines deployment plans in education, training, research and development in the academic and industrial sectors.
This article describes in very general terms and for a broad audience the basic principles, functionalities, and corresponding algorithms intergrated in the program, and presents its application to a few materials representative of different fields of research where this general approach to the modelling of compositional disorder in crystalline solids could become an essential tool.
10.7554/eLife.08208.004 Figure 2. Overview of MCM's working principle and functionalities: A microbial community model is specified using human-readable configuration files in terms of metabolites, reactions, the metabolic potential of cell species and any additional environmental variables.
This chapter discusses the EONS object library, as well as two example models to illustrate the principles and functionalities of EONS.
Design oriented knowledge work was decomposed according to the principles of functionality and measurability.
Conceived to suit the requirements of those professionals, Bell & Ross watches meet four basic principles: legibility, functionality, precision and water-resistance.
A size that is suitable for everyday use, in line with the four fundamental Bell & Ross principles: readability, functionality, accuracy and water-resistance.
