Sentence examples for principle for targeting from inspiring English sources

Therefore, this kind of drug might constitute a very interesting new therapeutic principle for targeting both inflammation and pathological fibrosis and hypertrophy in the context of chronic heart failure.

Studies with Nutlins provided in vitro and in vivo proof-of-principle for targeting p53 MDM2 interaction for cancer therapy.

Importantly, COXibs were found to reduce the incidence of both familial and sporadic disease, providing important proof-of-principle for targeting COX/PG signaling [ 66- 69].

We provide proof-of-principle for targeting Cav-1-regulated polyamine uptake as a strategy to fight unwanted VSMC proliferation as observed in restenosis.

We demonstrate that caveolin-1 negatively regulates vascular smooth muscle cell polyamine uptake and show that caveolin-1-regulated polyamine uptake is critical for proliferative advantage of caveolin-1 deficient cells, providing proof-of-principle for targeting this mechanism as a strategy to fight unwanted proliferation.

Pinch principles are deployed for targeting, design and operation-guiding purposes, balancing the heat and mass transfer in a second generation CES of parallel type.

To provide a proof of principle for our targeting methodology, we used it to knock in an HA tag in the LRRK gene.

Functionalized DNA polyintercalators that bind to DNA in a sequence-selective manner represent, at least in principle, an attractive strategy for targeting cellular DNA.

MPs voted by 285 to 272 against a government motion seeking support, in principle, for a targeted response to a suspected chemical attack by President Assad's forces last week.

Earlier this year, the FTC updated its recommended principles for behavioral targeting.

To date, the Federal Trade Commission has issued a set of recommended principles for behavioral targeting and left companies and trade groups to regulate themselves.