Sentence examples for principle disruption from inspiring English sources
In principle, disruption of BBB renders microvascular wall more susceptible to changes in cortical extracellular milieu, which might have an influence on NVC that could outlast a migraine attack since upregulation of metalloproteases can last for up to 48 hours after CSD [ 14].
We can understand their internal principles; disruptions grow out of latent tensions.
In this study we present a new drug delivery principle – photochemical disruption of endocytic vesicles in specific regions of the body, for improving internalization of later applied macromolecular drugs.
I think that I am always amazed at how when I'm talking to people, I'm continually saying, oh, OK this is how they use these principles of disruption.
I am here to tell you that, while there are many success stories based on these principles, successful disruption need not depend wholly on a winner/loser scenario.
"The challenge that we face -- making health care affordable and conveniently accessible to most people -- is not unique to health care," Christensen wrote in his 2008 book the The Innovator's Prescription, where he proposes an approach to reform based on the principles of disruption.
Here we present a new drug delivery concept based on photochemical internalization-principle – photochemical disruption of endocytic vesicles before delivery of macromolecules, leading to an instant endosomal release instead of detrimental stay of the molecules in endocytic vesicles.
Overall, Parmap represents a perfect incarnation of the "propagate the concept with minimal disruption" principle introduced in Cole's algorithmic skeleton manifesto.
Uber used a similar principle in their disruption of the taxi industry.
If this is the case, then only Freud can explain why in the BEC's Investing Principles the word disruption is not mentioned even once.
The present study provides the first proof-of-principle evidence that disruption of the titin reading frame due to a truncating DCM mutation can be restored by exon skipping in both patient cardiomyocytes in vitro and mouse heart in vivo, indicating RNA-based strategies as a potential treatment option for DCM.
