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In addition, multistep reactions are, in principle, difficult to perform on these platforms, confining their applicability to molecular genotyping and a few other assays.
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A performance modelling analysis is therefore difficult to perform.
Proof-of-principle studies to measure drug effect on target are highly desirable during early drug development, but are difficult to perform.
Meaning a task very difficult to perform, it said.
But clinical trials are difficult to perform with children.
The stent procedure is extremely difficult to perform.
One reason is that it's difficult to perform.
It has been difficult to perform tracheal allotransplantation without immunosuppression.
This model makes it difficult to perform collaborative research efforts.
It is also difficult to perform in small bones [40].
Hence, it is difficult to perform a completely fair comparison.
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