The discrete maximum principle assumption (DMP) We assume that the matrix B = ( b ( φ i, φ j ) ) is an M-Matrix [8, 9].
The principle assumption of our study is that the pathways that relevant to the disease mechanism should be consistently discovered in a number of independent studies.
The principle assumption that allowed the inclusion of single-arm before-and-after observational studies was that the placebo effects, the α i s, were exchangeable or that there was no a priori reason that there would be systematic differences between these effects.
Significant deviations of this statistic from zero indicate a violation of one or both of the two principle assumptions of the method, absence of selection and constant population size.
That is, he repeatedly invokes the alluring, but fundamentally unsound, principle that simple ideas about forecasting and prediction from one field, like economics, can readily be appropriated and applied to completely different fields, without a solid grounding in the principles, assumptions, and methods of those fields.
Due to the diversity of underlying principles, assumptions, and scoring systems, we defined the prediction agreement, i.e. the number of methods that agree on a certain miRNA target prediction, as a measure of confidence in the target prediction.
In this respect, the validity of the "self-preference principle"—the assumption that self-interest is the motivation of all human action is questionable.
The keystone of Morgenthau's realist theory is the concept of power or "of interest defined in terms of power," which informs his second principle: the assumption that political leaders "think and act in terms of interest defined as power" (5).
In principle, the assumption is tenable, based on the observation that the ACh volley output and the overall EPSC amplitude and properties remain reasonably constant over time.
One advantage of studies of substance use phenotypes, such as tobacco and alcohol use, is that in principle this assumption can be tested directly by assessing the relationship between genotype and the outcome of interest in unexposed individuals (e.g., never smokers).
We assumed that the polygenic component P i (t) was identical for both ER-negative and ER-positive disease (that is, represented by the same set of polygenes conferring the same relative risks), although in principle this assumption could be relaxed.
