Sentence examples similar to principle assays from inspiring English sources

We observed that while TaqMan probe had higher hybridization efficiency, shared-stem molecular beacons had lower background when the probe type was exchanged in the proof-of-principle assays.

The combined advantage of the two self-quenched probes was demonstrated in the three proof-of-principles assays.

All probes used for the three proof-of-principles assays were designed to match with wild-types except in the detection of lamivudine- and adefovir-resistant mutations in HBV, where probe for amino acid 180 matched with mutant type of M instead of the wild-type of L. The wild-type samples were always used as positive controls and water was used as no-template control (NTC) in these assays.

Compounds known for their antioxidant properties were tested on the zebrafish embryos in proof-of-principle assays, in which treatment with apomorphine-S provided the biggest increase in survival (66%).

Compounds known for their antioxidant properties were tested on the zebrafish in proof-of-principle assays in order to determine the suitability of the assay for a more high-throughput drug screen in the future.

(B ) A proof-of-principle assay was conducted using known methylated DNA-binding proteins on a pilot protein microarray.

For this pilot "proof-of-principle" assay we selected the drug rapamycin because of its extensively studied impact on translation initiation.

To determine whether the SOX11-C1 allowody allow intracellular detection of SOX11 in flow cytometry, we performed a proof-of-principle assay and analyzed well-defined lymphoma and EOC cell lines.

In principle, similar assays should also be possible with eukaryotic cells and for many other chromosomal proteins such as for example hexameric helicases and certain transcription factors.

This assay is based on the following principle: This assay, based on the micro-method of calcium determination using O-cresolpthalein complexone dye (12), involves the reaction of calcium with O-CPC to produce a purple complex at pH 10-12 with an absorbance maximum at 575 ± 5 nm.

In principle this assay is similar to the RIA except that an enzyme system, instead of radioactivity, is used as an indicator of an antigen-antibody combination.